Prescriptions of 10 most common antidepressants top 109M: a breakdown

There are more than 109 million prescriptions for the 10 most commonly used antidepressants in the U.S., according to data from Definitive Healthcare. 

The healthcare intelligence company compiled medical claim data published monthly in the U.S. to find the 10 most commonly prescribed antidepressants as of June 2022.

 

Here are the 10 most-prescribed antidepressants and how many prescriptions there are of each.

 

Medication

Number of prescriptions

  1. Sertraline hydrochloride

18,337,255

  1. Trazodone hydrochloride

15,175,105

  1. Bupropion hydrochloride

14,849,877

  1. Fluoxetine

12,925,013

  1. Duloxetine

11,168,323

  1. Escitalopram

9,632,164

  1. Venlafaxine hydrochloride

7,995,409

  1. Citalopram hydrobromide

7,181,357

  1. Escitalopram oxalate

6,958,167

  1. Amitriptyline hydrochloride

5,107,340

Total

109,330,010

 

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