The cost of opioid use disorder, by state

Opioid use disorder cost the United States $3.8 trillion in 2024, according to analysis from Avalere Health. 

In an analysis published May 20, the healthcare firm broke down the average cost of OUD by category and state. Most of the costs of OUD are patient burdens — decreased quality of life, disability, criminal justice involvement and other costs. 

Excluding patient burdens, OUD cost the U.S. $934 billion in 2024, including $438 billion in lost productivity. 

On average, each OUD case costs $694,664. In some states, this average is twice as high. 

Here is the total cost per OUD case in each state: 

1. District of Columbia: $2,449,643
2. Maryland: $1,464,768
3. West Virginia: $1,216,836
4. Rhode Island: $1,113,264
5. Ohio: $1,027,203
6. Connecticut: $901,139
7. New York: $851,819 
8. New Hampshire: $834,013
9. Illinois: $831,807 
10. Maine: $828,965
11. Tennessee: $808,634
12. Massachusetts: $803,511
13. Missouri: $793,781
14. New Mexico: $788,194
15. Minnesota: $765,316
16. Wisconsin: $753,757
17. North Carolina: $753,322
18. Michigan: $742,799
19. Georgia: $736,361
20. Delaware: $728,511
21. Pennsylvania: $728,202
22. Wyoming: $714,641
23. Kentucky: $709,441
24. Florida: $709,050
25. Vermont: $702,310
26. Indiana: $670,763
27. South Carolina: $657,437
28. Virginia: $647,877
29. New Jersey: $646,109
30. Arizona: $628,009
31. Alaska: $600,478
32. Colorado: $591,891
33. Utah: $568,856
34. Oklahoma: $563,948
35. Alabama: $559,899
36. Kansas: $551,464
37. Arkansas: $551,462
38. Nebraska: $551,451
39. California: $536,027
40. Nevada: $514,904
41. Iowa: $514,601 
42. Washington: $493,501
43. Hawaii: $487,922 
44. Montana: $479,238
45. North Dakota: $479,203
46. South Dakota: $479,197
47. Texas: $477,189
48. Oregon: $465,037
49. Mississippi: $464,192
50. Louisiana: $432,034
51. Idaho: $419,527 

Read the full report here.