Opioid use disorder diagnosis rate climbs nearly 33% in 3 years

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The rate of opioid use disorder diagnoses among commercially insured patients rose 32.7% nationwide between 2022 and 2025, FAIR Health found in its latest analysis of commercial health claims.

The national rate reached 596 patients with an opioid use disorder diagnosis per 100,000 commercially insured patients receiving medical services in 2025, up from 449 in 2022. The findings were published as part of FAIR Health’s annual Opioid Tracker update, according to an Oct. 14 news release from the organization.

Here are four things to know:

1. Tennessee recorded the highest rate in 2025, with 1,551 patients with an opioid use disorder diagnosis per 100,000 patients. West Virginia ranked second at 1,528, followed by Mississippi at 1,373, Arkansas at 1,320 and Delaware at 1,256.

2. Alcohol and substance abuse services and treatments made up 39% of claim lines tied to opioid use disorder diagnoses nationally in 2025. Methadone treatment under procedure code G2067 represented 9.4% of total allowed amounts, averaging $243 per service.

3. Patients ages 41-50 represented the largest share of those diagnosed, at 28.1%. Men accounted for 56.1% of patients with opioid use disorder diagnoses, while women accounted for 43.9%.

4. Among specialties treating opioid use disorder, nurse practitioners saw the largest increase in their share of claim lines from 2022 to 2025, at 67%. Psychiatric nurses and emergency medicine followed with increases of 47% and 44%, respectively.

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