FDA clears breakthrough fast-acting oral treatment for depression

Auvelity, an oral medication capable of improving major depression symptoms in one week, was approved by the FDA  Aug. 19.

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The medication was created by Axsome Therapeutics, a pharmaceutical company that develops treatments for central nervous system disorders. 

“[Auvelity] represents the first new oral non-monoamine-based mechanism of action approved to treat major depressive disorder in over sixty years,” Maurizio Fava, MD, psychiatrist-in-chief, Massachusetts General Hospital, said in a Aug.19 news release from Axsome. 

“Given the debilitating nature of depression, the efficacy of Auvelity observed at one week and sustained thereafter may have a significant impact on the current treatment paradigm for this condition,” Dr. Fava said.

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